Citalopram is a prescription medicine used in adults to treat depression. Citalopram is also used to treat major depressive disorder (MDD). Citalopram belongs to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). Citalopram (Celexa) is a well-tolerated SSRI for depression. Learn about the 40mg daily dose limit due to QT prolongation and how it compares to escitalopram. Citalopram (Celexa) is a medication that treats depression. It increases the amount of serotonin in your brain. Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7][9] It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social anxiety disorder. [7] Celexa (citalopram hydrobromide) used to treat the symptoms of depression. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. Learn about citalopram (Celexa) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Overview: Citalopram is used to treat depression. It is thought to work by increasing the amount of a natural chemical called serotonin in the brain. Common side effects may include nausea, changes. Celexa is a selective serotonin reuptake inhibitor (SSRI) that blocks the reuptake of serotonin (5-HT) by the nerves of the central nervous system, which enhances serotonergic activity. Take this medicine only as directed by your doctor, to benefit your condition as much as possible. Celexa (citalopram) is a medication that’s commonly prescribed for depression. It’s generally well tolerated, but it has some side effects to be aware of. Common side effects of Celexa include nausea, dry mouth, and sleep changes. Sexual side effects, such as erectile dysfunction, are also possible.